Light as a zeitgeber
External time cues are central to that counteraction. The strongest external zeitgeber of the circadian rhythm is light, and short-wavelength blue light in particular. It acts through melanopsin-containing retinal ganglion cells on the suprachiasmatic nucleus in the hypothalamus – the central pacemaker of our body clock, which coordinates the sleep-wake rhythm, hormone release, body temperature and time-of-day dependent performance, among other things.